Read a new publication from Oncowitan: The small GTPase Rac1 is frequently overexpressed and hyperactivated in hepatocellular carcinoma (HCC). The selective targeting of this protein, with RNA-based regulators and small molecules lead to prominent antitumor effects. A novel approach to combat chemoresistance and metastasis

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Overexpressed or hyperactivated Rac1 as a target to treat hepatocellular carcinoma, Pharmacological Research (2022)

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